What Other Drugs Will Affect Desiccated Thyroid
Tell your doctor about all medicines you use, and those you start or stop using during your treatment with desiccated thyroid, especially
birth control pills or hormone replacement therapy
a blood thinner such as warfarin
insulin or diabetes medication you take by mouth
medications that contain iodine
salicylates such as aspirin, Nuprin Backache Caplet, Kaopectate, KneeRelief, Pamprin Cramp Formula, Pepto-Bismol, Tricosal, Trilisate or
steroids such as prednisone and others.
This list is not complete. Other drugs may interact with desiccated thyroid, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible interactions are listed in this medication guide.
What Are The Side Effects Of Thyroxine
Side effects of thyroxine are generally rare but can be serious. Thyroxine is a hormone replacement drug therapy that is typically well-tolerated by the body, and when side effects do occur, it is usually because the dose is too high. Hair loss can occur when first taking the drug, but it is usually temporary. Uncommon, but serious, side effects that can happen include increased sweating, mood changes, shaking, and trouble sleeping. In very rare cases, a patient might experience chest pain, irregular heartbeat, seizures, or possibly an allergic reaction.
In general, most people will have little to no side effects when taking thyroxine, even during pregnancy. Some people will have hair loss during the first few months on the medication, but this usually goes away once the body has had a chance to adjust. Also, women taking the drug might find that they have irregular menstrual cycles.
When the body has too much thyroid hormone from an overdose of thyroxine, it can lead to hyperthyroidism. Some of the uncommon side effects include increased sweating, sensitivity to heat, diarrhea, and shaking. It can also cause mood changes such as nervousness, anxiety, and irritability. Additionally, it can result in headaches, shortness of breath, muscle cramps or weakness, and trouble sleeping. Further side effects can be unusual weight loss or gain, a change in appetite, and vomiting.
How Should This Medicine Be Used
Levothyroxine comes as a tablet and a capsule to take by mouth. It usually is taken once a day on an empty stomach, 30 minutes to 1 hour before breakfast. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take levothyroxine exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor.
Swallow capsules whole do not chew or crush them. Do not remove the capsule from the package until you are ready to take it.
Take the tablets with a full glass of water as they may get stuck in your throat or cause choking or gagging.
If you are giving levothyroxine to an infant, child, or adult who cannot swallow the tablet, crush and mix it in 1 to 2 teaspoons of water. Only mix the crushed tablets with water do not mix it with food or soybean infant formula. Give this mixture by spoon or dropper right away. Do not store it for later use.
Your doctor will probably start you on a low dose of levothyroxine and gradually increase your dose.
Levothyroxine controls hypothyroidism but does not cure it. It may take several weeks before you notice a change in your symptoms. Continue to take levothyroxine even if you feel well. Do not stop taking levothyroxine without talking to your doctor.
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How And When To Take Levothyroxine
Take levothyroxine once a day in the morning, ideally at least 30 minutes before having breakfast or a drink containing caffeine, like tea or coffee.
Food and caffeinated drinks can both stop your body taking in levothyroxine properly so it does not work as well.
If you stop taking levothyroxine your symptoms are likely to come back.
What Are The Side Effects Of Thyroid Medicine
Side effects of thyroid medicine can occur when a patient is taking too much or not enough, causing abnormal levels of thyroid hormone. There can also be concerns about interactions with other foods or dietary components like iodine. The precise side effects can depend on the medication and the concentrations of thyroid hormone in the body but may include headaches, poor thermoregulation, weight changes, and fatigue. Patients should discuss side effects with their medical providers, as they may indicate that the medication is not working as intended.
People who are not producing enough thyroid hormone need to take a synthetic medication to replace the function of this gland. While they have low hormone levels they may have symptoms like muscle pains, extreme fatigue, and constipation. These can persist while the dosage of thyroid medicine is slowly adjusted upward to find the point at which it is effective. Patients may spend weeks or months getting used to the medication, during which they attend regular follow-up appointments to see if they need higher doses.
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Interactions With Other Medicines And Other Forms Of Interactions
Oral anticoagulants, coumarin or indandione derivative, e.g. warfarin.
SSRIs, e.g. sertraline.
Insulin and antidiabetic agents, e.g. sulfonylureas.
Beta-adrenergic blocking agents, e.g. propranolol.
Ion-exchange resins, e.g. cholestyramine, sodium polystyrene sulphonate or colestipol.
Corticosteroids, e.g. prednisolone and dexamethasone.
Antiepileptics, e.g. phenytoin, carbamazepine and barbiturates.
Antibacterials, e.g. rifampicin and ciprofloxacin.
Androgens and anabolic steroids.
Medicines that (partially inhibit the peripheral transformation of T4 to T3.
Weight loss drugs.
How Should I Take Desiccated Thyroid
Take desiccated thyroid exactly as prescribed by your doctor. Follow all directions on your prescription label. Do not take this medicine in larger or smaller amounts or for longer than recommended.
While using desiccated thyroid, you may need frequent blood tests.
To be sure this medication is helping your condition, your blood may need to be tested often. Visit your doctor regularly.
Keep using this medicine as directed, even if you feel well. You may need to take thyroid medication for the rest of your life.
If you need surgery, tell the surgeon ahead of time that you are using this medicine. You may need to stop using the medicine for a short time.
Store at room temperature away from moisture and heat.
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Levothyroxine 25 Micrograms Tablets
This information is intended for use by health professionals
Levothyroxine 25 micrograms Tablets
Each tablet contains 27.8 micrograms of levothyroxine sodium equivalent to 25 micrograms of levothyroxine sodium anhydrous.
For the full list of excipients, see section 6.1
White, circular, convex tablets marked TX25 on one face and CP on the reverse.
Levothyroxine sodium is used in adults and children for the treatment of thyroid deficiency states.
In younger patients, and in the absence of heart disease, a serum Levothyroxine level of 70 to 160 nanomols per litre, or a serum thyrotrophin level of less than 5 milli-units per litre should be targeted. A pre-therapy ECG is valuable because ECG changes due to hypothyroidism may be confused with ECG evidence of cardiac ischaemia. If too rapid an increase in metabolism is produced dosage must be reduced, or withheld, for a day or two, and then re-started at a lower dose level.
Adults: Initially, 50 to 100 micrograms daily , preferably taken before breakfast or your first meal of the day. Adjust at three to four week intervals by 50 micrograms until normal metabolism is steadily maintained. The final dose may be up to 100 to 200 micrograms.
Elderly: as for patients aged over 50 years
Patients over 50 years with cardiac disease:
For patients aged over 50 years, with or without cardiac disease, clinical response is probably a more acceptable criteria of dosage rather that serum levels.
Thyroid Hormone Replacement Drugs
Levothyroxine is a type of thyroid hormone replacement drug that is often used to treat hypothyroidism. Brand names for levothyroxine include Synthroid, Levoxyl, and Tirosint.
Natural dessicated thyroid is also used to treat hypothyroidism. For some people, NDTs work better than levothyroxine, and many people prefer them because they are more natural. Brand name NDTs include Armour and Nature-Throid.
Usually, people begin thyroid hormone therapy with a low dose that is gradually increased. In part, this is because hypothyroidism progresses over time. But starting therapy with a low dose is also helpful for reducing the risk of overmedication.
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If You Forget To Take It
If it is almost time for your next dose, skip the dose you missed and take your next dose when you are meant to.
Otherwise, take your dose as soon as you remember, and then go back to taking it as you would normally.
Do not take a double dose to make up for the dose that you missed.
If you are unsure about whether to take your next dose, speak to your doctor or pharmacist.
If you have trouble remembering when to take your medicine, ask your pharmacist for some hints.
How Does Antithyroid Medication Work
Thyroxine is a body chemical made by the thyroid gland. It is carried around the body in the bloodstream. It helps to keep the body’s functions working at the correct pace. Many cells and tissues in the body need thyroxine to keep them working correctly.
‘Hyperthyroidism’ means an overactive thyroid gland. When the thyroid gland is overactive it makes too much thyroxine. The extra thyroxine causes many of the body’s functions to speed up.
Thionamides such as carbimazole reduce the amount of hormone released by the thyroid gland. Carbimazole does not affect the thyroxine which is already made and stored, but reduces further production. Therefore, it may take four to eight weeks of treatment for your thyroxine level to come down to normal.
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Are There Any Side Effects Caused By Thyronorm
Generally, this medicine does not cause any side effects. But if a patient takes an overdose of the medicine, it can cause side effects. Thyronorm tablet side effects can get cured on their own. But if any of the side effects start getting serious, we must contact our doctor immediately. The common side effects experienced by patients are
- Mood swings, etc.
If anyone is facing any of these side effects for a long time, they must consult with the doctor as soon as possible. This might be caused due to an inappropriate dosage of the medicine but can be cured easily.
What Is In This Leaflet
This leaflet answers some common questions about EUTROXSIG tablets.
It does not contain all the available information about the medicine.
It does not take the place of talking to your doctor or pharmacist.
All medicines have risks and benefits. Your doctor has weighed the risks of you taking EUTROXSIG against the benefits they expect it will have.
Ask your doctor or pharmacist if you have any concerns about taking this medicine.
Keep this leaflet with the medicine. You may need to read it again.
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Desiccated Thyroid Side Effects
Get emergency medical help if you have any signs of an allergic reaction: hives difficult breathing swelling of your face, lips, tongue, or throat.
Less serious side effects may include temporary hair loss .
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
Pregnancy And Breastfeeding While Taking Synthroid
Heres some information on pregnancy and breastfeeding while taking Synthroid.
Pregnancy. Its generally safe to use Synthroid while pregnant. Taking Synthroid doesnt appear to increase the risks of birth defects or pregnancy loss. But if you become pregnant during your treatment, your doctor may need to increase your dose of Synthroid. This is because pregnancy can sometimes increase the need for thyroid hormones.
Keep in mind that untreated hypothyroidism can be dangerous during pregnancy.
Breastfeeding. It isnt known whether its safe to take Synthroid while breastfeeding. The drug is believed pass into human breast milk. But it isnt known what effects, if any, this could have on a breastfed child. Talk with your doctor about the risks and benefits of treatments for your condition while breastfeeding.
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Can Levothyroxine Hurt Your Kidneys
A study by Shin et al. in 2012 reported a significantly higher incidence rate of end-stage renal disease among SCH patients not treated with levothyroxine . Treatment with levothyroxine was associated with a delay in progression to CKD stage 5 or ESRD, as well as overall renal function preservation .
Can I Take Levothyroxine If Im Pregnant Or Breastfeeding
If you become pregnant while taking levothyroxine, do not stop taking the medicine without your doctor’s advice. Having low thyroid hormone levels during pregnancy could harm both mother and baby. Your dose needs may be different during pregnancy.
Tell your doctor if you are breastfeeding. Your dose needs may be different while you are nursing.
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What Are The Side Effects Of Levothyroxine Sodium
Reported side effects of levothyroxine sodium include:
- Not eating
- Skin problems, such as red, inflamed skin
- Increased drinking and urination and
- Increased activity level.
FDA encourages you to call your veterinarian if you think your dog is having a side effect from levothyroxine sodium. A side effect associated with a drug is called an adverse event. Adverse events also include a lack of effectiveness and reactions in people who handle the drug. Call your healthcare provider if you have a reaction to levothyroxine sodium.
FDA also encourages you to work with your veterinarian to report any adverse event – in either pets or people – associated with levothyroxine sodium or any product defect such as defective packaging or the drug is off-color. How to Report Animal Drug and Device Side Effects and Product Problems.
Remember to keep the drug in a secure location out of reach of children, dogs, cats, and other animals to prevent accidental ingestion or overdose.
Sometimes, a condition called thyrotoxicosis may develop dogs receiving levothyroxine sodium if:
- The dose is too high
- The dog has an underlying illness that affects the bodys ability to break down the drug or
- The dog is very sensitive to the drug.
Signs of thyrotoxicosis include panting, nervousness, hyperactivity, a rapid pulse, increased drinking and urination, vomiting, diarrhea, and weight loss despite having an increased appetite. Call your veterinarian if you see these signs in your dog.
How Do I Take Antithyroid Medicine
Getting the right balance of thyroid hormone in your blood can take time.
Doctors have two main methods of trying to get the balance right. The first involves taking an initial high dose of carbimazole to reduce the amount of thyroxine in your blood. This dose is taken until the hormone levels in your blood have stabilised, usually about four to eight weeks later. Because your body needs a certain amount of thyroxine to function properly, the high dose is then slowly decreased. Usually, your hormone levels will be checked by a blood test every month or so. The dose of medicine you are taking will be changed depending upon the results of your thyroid hormone levels. The aim of this treatment is to keep you on the lowest level of antithyroid medicine necessary. This treatment method is called ‘titration’.
It can be difficult for a doctor to judge just the right dose of carbimazole to give in each case. Too much treatment may make the thyroxine level go too low. Not enough treatment means the level remains higher than normal. This is the reason for the regular blood tests and careful monitoring.
The second option is to deliberately take a high dose of carbimazole each day. This stops the thyroid gland making any thyroxine. Your doctor can then prescribe a daily dose of thyroxine to keep the blood level of thyroxine normal. This ‘over-treatment’ coupled with taking replacement thyroxine is called ‘block and replace’ and is a popular option.
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Can Synthroid Cause Dry Mouth
But dry mouth can be a symptom of hypothyroidism, which Synthroid is used to treat. With treatment, dry mouth will likely go away.
If you have additional questions about dry mouth, talk with your doctor or pharmacist.
Before You Start To Take It
Tell your doctor if:
- overactive thyroid gland
- heart problems such as cardiovascular disorder
- high blood pressure
- long-standing hypothyroidism, an underactive thyroid gland.
- problems absorbing nutrients from the gastrointestinal tract
If you have not told your doctor about any of the above, tell them before you start to take any EUTROXSIG.
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