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How To Read Thyroid Lab Test Results

Is It Possible To Reduce Thyroid Peroxidase Antibodies If They Are Elevated

How to Interpret Your THYROID Lab Results


And this might just be the most important part of this article.

After all, if you know that TPO antibodies are causing problems in your body, doesn’t it make sense to try and do something about them?

Of course!

But here’s the problem:

From the perspective of your doctor, there’s nothing that can be done about elevated thyroid peroxidase antibodies.

Doctors take what is called the “sit and wait” approach to managing people who have elevated thyroid antibodies.

They sit and wait until your own body damages the thyroid gland to the point that you need prescription medication.

Just because your doctor doesn’t have any medical treatment options for you doesn’t mean you can’t do anything, though!

Seeing a doctor is important, for sure, but when it comes to managing your thyroid antibodies you are probably going to be on your own.

It may sound difficult but it actually isn’t.

Making some changes to your lifestyle can have an impact on your immune system and thyroid health and this may directly help your antibodies.

Doing things like changing the food that you eat can have a huge impact on your antibody levels.

Avoiding foods that are known to be inflammatory is a great place to start.

Eating foods that are known to possess natural anti-oxidants and plant-based nutrients is also a wise decision.

You can also focus on improving your lifestyle.

And guess what?

You don’t really need a doctor to tell you that eating fruits and vegetables is a good thing, right?

How To Test Your Thyroid Function

You can test your thyroid function using a blood sample. The two main ways to collect a blood sample are:

  • a venous blood test a trained professional will use a needle to puncture a vein, usually in your arm, to collect a blood sample.
  • a finger-prick blood test using a lancet, you can prick your own finger and collect a small blood sample.

What Information Will I Receive From The Tool

Once you enter your information, the thyroid function test analyzer will tell you if your result is low, optimal, or high and what that might mean. Youll also learn a little bit about the test, why its done, and what it measures.

Patients with thyroid cancer, pregnancy or pituitary disorders must seek a specialist’s care.

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What Are Thyroid Blood Tests And Why Are They Taken

Thyroid blood tests are used to tell if your thyroid gland is functioning properly by measuring the amount of thyroid hormones in your blood. They are done by withdrawing blood from a vein in your arm. These blood tests help to diagnose thyroid diseases.

The thyroid is a butterfly-shaped gland located in the front part of your neck. Its job is to produce thyroid hormones, which travel through your bloodstream and regulate many aspects of your bodys metabolism, including temperature, weight, and energy.

Thyroid blood tests show if you have:

  • Hyperthyroidism: Overactive thyroid producing more thyroid hormones than your body needs. Hyperthyroidism speeds up your metabolism, which can cause weight loss, rapid heartbeat, insomnia, puffiness around the eyes, anxiety and other symptoms. The most common cause of hyperthyroidism is Graves disease.
  • Hypothyroidism: Underactive thyroid producing too few thyroid hormones. Hypothyroidism slows down your metabolism, which can cause weight gain, menstrual irregularity, dry and puffy skin, fatigue and other symptoms. The most common cause of hypothyroidism is Hashimotos disease.

Thyroid blood tests are used to diagnose thyroid disorders associated with hyper- or hypothyroidism. These include:

Canadian Labs And Ranges:

How To Read Your Thyroid Panel Results

Serum Iron Optimal results are usually in the mid-20s for women, upper 20s and higher for men)

Percent Saturation: same as US observations i.e. .35/35% for women is the ideal .38/38% and often a little higher for men.

TIBC: when range is umol/L > 45-77, low 60s is noted when iron is looking good. If range is 50-70 umol/L, usually 1/4th above bottom of range.

Ferritin: range is often 15-200, and optimal for most women is 70-90, for men its 110-120.

Note: 60% of patients have a hematologic or neurologic response to B12 supplementation at a level < 148 pmol/L

FOR THOSE WHO USE MATHheres how to find those areas of of lab ranges for thyroid, adrenals and TIBC

Top 1/4 of the range ** Math to do this, subtract the highest number in range from lowest number in range, divide by 4. Subtract this number to the highest number in range

Mid range ** Add lowest number in range to highest number in range. Divide by 2.

Bottom ΒΌ of the range: Subtract the right number of the range from the left number of the range, divide by 4. Add this number to the left number in the range



Other countries to order labs shown here :

A great article about the fallacy of ranges:

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No Thyroid Therapy Gt: Functional Thyroid Capacity

  • NOTE: GT will only calculate properly outside of thyroid hormone therapy. Above the results, verify that that youve correctly selected nothing or T4-substitution.

In subclinical hypothyroidism, judging by an elevated TSH with a T4 anywhere within reference alone is not enough to diagnose loss of thyroid function. Two lab 6 weeks apart, analyzed via SPINA, may confirm suspicion of permanently damaged thyroid tissue that is unable to secrete more T4 in response to elevated TSH.

The lower GT is more sensitive to low thyroid function than ultrasound calculation of thyroid volume.

In Hashimotos thyroiditis, the thyroid may or may not shrink or expand while losing GT. Fibrosis and death of cells that produce hormone will reduce the thyroid glands ability to respond to TSH stimulation, and therefore GT will be significantly lower, or low within reference.

If GT is high, it could be from Graves disease antibodies stimulating the thyroid, infectious thyroiditis, or a toxic thyroid nodule that is autonomously secreting hormone.

GT can be affected by iodine intake because thyroid hormones are synthesized by iodine distinctive patterns appear with iodine deficiency and excess.

Where To Get A Thyroid Function Test

NHS thyroid function test The NHS offer blood tests which can be done at your GPs or a local hospital. A trained nurse or doctor will take your blood, usually a venous sample.

Home thyroid function test Its possible to order a home thyroid function test kit online and do it yourself. For this test, youll use a lancet to collect a finger-prick blood sample. Your results will be reviewed by a GP and are available for you to view online.

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What Are Thyroid Hormones

The thyroid gland produces hormones that are essential for normal body metabolism. Blood testing is now commonly available to determine the adequacy of the levels of thyroid hormones. These blood tests can define whether the thyroid gland’s hormone production is normal, overactive, or underactive.

The thyroid gland is located in the lower part of the neck, below the Adam’s apple.The gland wraps around the windpipe and has a shape that is similar to a butterfly – formed by two wings and attached by a middle part .

The thyroid gland uses iodine to produce thyroid hormones.

  • The two most important thyroid hormones are thyroxine and triiodothyronine , which account for 99.9% and 0.1% of thyroid hormones present in the blood respectively.
  • However, the hormone with the most biological activity is T3.
  • Once released from the thyroid gland into the blood, a large amount of T4 is converted into T3 – the active hormone that affects the metabolism of cells.

What Is A T3 Test

How To Read Your Thyroid Panel Results

T3 TestsT3 tests measure triiodothyronine levels in the blood. A Total T3 test measures the bound and free fractions of triiodothyronine. Hyperthyroid patients typically have an elevated Total T3 level. T3 tests can be used to support a diagnosis of hyperthyroidism and can determine the severity hyperthyroidism.

In some thyroid diseases, the proportions of T3 and T4 in the blood change and can provide diagnostic information. A pattern of increased T3 vs T4 is characteristic of Graves disease. On the other hand, medications like steroids and amiodarone, and severe illness can decrease the amount of thyroid hormone the body converts from T4 to T3 resulting in a lower proportion of T3.

T3 levels fall late in the course of hypothyroidism and therefore are not routinely used to evaluate patients with underactive or surgically absent thyroid glands.

Measurement of Free T3 is possible, but is often not reliable and therefore may not be helpful.

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Side Effects And Aftercare

A blood draw is a routine, minimally invasive procedure. During the days immediately after the blood draw, you may notice slight bruising or soreness at the area where the needle was inserted. An ice pack or an over-the-counter pain reliever can help ease your discomfort.

If you experience a great deal of pain, or if the area around the puncture becomes red and swollen, follow up with your doctor immediately. These could be signs of an infection.

Signs You Should Do A Thyroid Function Test

If any of these hormones are out of balance it can lead to a thyroid disorder and cause a wide range of symptoms. If youre experiencing any of these symptoms its really important to check your thyroid function. Its also common for thyroid disorders to run in families so its particularly important to test your thyroid function if you think you might be at risk. You can test your thyroid function as part of our women’s hormones blood test.

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What Is A Normal Level For Thyroid Peroxidase Antibodies On My Lab Tests

When you get your thyroid peroxidase lab results you will see a range of what is considered “normal”.

The range is usually somewhere between 0 and 34 IU/mL .

If your thyroid peroxidase antibodies fall within the 0 to 34 range they will be considered “normal” and they won’t flag as high on your lab tests.

Any value that is higher than 34 IU/mL will flag as high and is an indication that thyroid dysfunction is likely on its way.

Despite this so-called “normal” range, there are a number of people who advocate for near-zero levels of antibodies.

The idea goes something like this:

Even though thyroid peroxidase antibodies of, let’s say, 25 IU/mL are technically “normal” wouldn’t it be better to have a value as close to zero as possible?

In other words, because the presence of any non-zero level of antibodies indicates a problem in the body, isn’t any level of thyroid antibodies a problem?

And the answer to this question is more complicated but I do tend to agree with the logic.

The presence of thyroid peroxidase antibodies is probably more likely to be problematic in the future than not and should, therefore, be taken seriously.

Because of this, I advocate for thyroid peroxidase levels as close to zero as possible.

Another way to think about this issue is like this:

Imagine that you are in the very EARLY beginning stages of developing Hashimoto’s thyroiditis.

Before you experience full blown Hashimoto’s you will experience moderate Hashimoto’s.

There Are 6 Additional Lab Bio Markers That I Like To Run With Patients

Pin on Me, me, me

#1 Sex hormone binding globulin- In women it should be in the 70-80 range and can be helpful for determining tissue levels of thyroid hormone

#2,#3,#4 and #5 are #6HS-CRP, ESR, Ferritin, Fibrinogen, Homocystein

Elevations in these markers indicates inflammation and are known as acute phase reactants. The CRP and ESR should be as low as possible, However Fibrinogen and Ferritin will often shoot up in cases of infection and inflammation and your Homocysteine levels should be less than 7.0.

Ok. the last thing we need to cover today are several conditions where the TSH can be so called normal but the patient can still be hypothyroid. When you look at your blood work reference ranges, you will notice that its a pretty big range it goes from .5-5.0 or even up to 6.0 on some labs.

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What Is Graves Disease Symptoms Causes Diagnosis And Treatment

Graves disease is an autoimmune disorder that causes hyperthyroidism, or the overproduction of thyroid hormones, according to the National Institute of Diabetes and Digestive and Kidney Diseases . The condition occurs when your immune system makes an antibody called thyroid-stimulating immunoglobulin , which causes the thyroid to make more thyroid hormone than your body requires. Without treatment, Graves disease can cause serious problems with the heart, bones, muscles, menstrual cycle, and fertility, among other complications.

Thyroid Lab Ranges Can Be Misleading

Hey everybody Dr Hagmeyer here and today I wanted to spend some time talking about the TSH test and why when ordered by itself or in conjunction with free T4 is incredible misleading.

I realized after shooting my last video titled 12 symptoms of Low thyroid that indicate the need for a full Complete Thyroid panel that there was just too much information that I didnt get a chance to talk about

So, in todays video I wanted to dive into some of these areas. There are 4 main things I want to review with you today.

  • Why you cant rely on TSH for Thyroid Health
  • The specific markers that make up a Complete thyroid panel and Where the ranges for those markers should fall ,
  • Some of the additional lab bio markers while not part of a thyroid panel, should be run because these markers if out of range will affect your thyroid.
  • Some of the common causes or conditions where the TSH is less than the reference range but a person is still hypothyroid.
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    What Do The Results Tell Us

    An enlarged thyroid also called a goiter can be a sign of an iodine deficiency that hasn’t yet affected the function of the thyroid. But it could also be a sign of an overactive thyroid or an underactive thyroid , where too many or too few hormones are made respectively.

    Nodules that can be felt from the outside may also be a sign of a thyroid problem. But sometimes people have an enlarged thyroid gland or nodules without it affecting the function of their thyroid gland.

    So this palpation examination can only tell us whether there might be a thyroid problem. Further tests and examinations are needed in order to be sure.

    What Are Normal Thyroid Hormone Levels


    The thyroid itself is regulated by another gland that is located in the brain, called the pituitary. In turn, the pituitary is regulated in part by the thyroid and by another gland called the hypothalamus.

    The hypothalamus releases a hormone called thyrotropin releasing hormone , which sends a signal to the pituitary to release thyroid stimulating hormone . In turn, TSH sends a signal to the thyroid to release thyroid hormones. If a disruption occurs at any of these levels, a defect in thyroid hormone production may result in a deficiency of thyroid hormone .

    Hypothalamus – TRH

    Thyroid – T4 and T3

    The rate of thyroid hormone production is controlled by the pituitary gland. If there is an insufficient amount of thyroid hormone circulating in the body to allow for normal functioning, the release of TSH is increased by the pituitary gland in an attempt to stimulate more thyroid hormone production. In contrast, when there is an excessive amount of circulating thyroid hormone, TSH levels fall as the pituitary attempts to decrease the production of thyroid hormone.

    • In persons with hypothyroidism , there is a continuously decreased level of circulating thyroid hormones.
    • In persons with hyperthyroidism , there is a continuously elevated level of circulating thyroid hormones.

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    Alternative And Complementary Therapies

    Certain lifestyle changes can also help improve Graves disease symptoms and boost general health, such as eating well and exercising, according to the Mayo Clinic. Weight gain may occur when hyperthyroidism is successfully treated, because the thyroid controls the metabolism, so eating healthfully and exercising are important. Graves disease can also cause brittle bones, and weight-bearing exercises can help maintain bone density.

    Stress may trigger Graves disease or make it worse, so stress-relieving practices can help, such as listening to music, taking a warm bath, or walking.

    What Are Thyroid Peroxidase Antibodies

    What I just described is what thyroid peroxidase does inside of the thyroid gland but this is completely different from thyroid peroxidase antibodies.

    If you’ve been told that you have thyroid peroxidase antibodies, also referred to as TPO antibodies, then this information applies to you.

    Your body creates antibodies to things that it wants to kill or get rid of.

    In the healthy state, you should really never see antibodies to any part of your own body or tissues.


    Because why would you want to get rid of something that is supposed to be in your body!

    Antibodies are usually created to help your body eliminate infections or viruses but they can sometimes be created by your immune system to target your own body.

    When this happens you are said to have an autoimmune disease .

    We can break apart the word to understand exactly what it means:

    Auto , immune , and disease .

    In the case of thyroid peroxidase antibodies, your own body is creating antibodies that target, damage, and destroy, the thyroid peroxidase enzyme.

    These antibodies are produced by the immune system and flow through your entire body until they find their target.

    Once they reach their target their goal is to destroy it.

    And because their target is located in the thyroid gland, your thyroid becomes the site of a war between your immune system and thyroid peroxidase.

    As you might imagine, this results in damage to your thyroid gland which can become permanent if the damage is severe enough.

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