Empower Offers Custom Thyroid Solutions
As is the usual in medicine, the answer to what thyroid medication is best for me? is not be a simple one, nor should it be: Thyroid USP, Levothyroxine, Liothyronine, and combinations in concert all carry a unique profile of advantages, disadvantages, and nuance. 75% of all medicated hypothyroidics still experience at least one symptom to varying extent,41 and it is absolutely imperative that healthcare providers have every resource and every tool at their disposal if a patient is to achieve an optimal quality of life.
This is why Empower offers as potent a tool-kit as possible: Thyroid USP, Levothyroxine, Liothyronine – with complete control over dose composition and strength, binder, filler, and excipient alternatives, and the ability to decide whether or not to utilize instant or extended release.
While it has been demonstrated that some people can experience unpleasant or sub-optimal results from combination therapy,42 there are also those who experience both qualitative43 and quantitative benefits/symptom relief.44 Everyones solution is unique, and considering that roughly 75% of all medicated hypothyroidics still experience at least one symptom of their disease to an extent,45 it follows that the treatment practices proclaimed as the universal gold standard in the past 46 might not be those that ought be exclusively used in the future.
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What Is The Difference Between Armour Thyroid And Levothyroxine
Q. I was on levothyroxine for about 30 years, and then I started having really bad side effects. It made me itch all over, as if bugs were biting me. Heartburn was a constant torment and my hair was falling out.
My doctor suggested Armour Thyroid, which is all natural. It has made a huge difference.
What Are Some Examples Of Natural Thyroid Hormone Replacement
Naturally derived thyroid preparations come from animals, usually pigs, cows, or sheep. Desiccated thyroid is a natural preparation, and it was the only treatment for hypothyroidism before levothyroxine was available. It has a characteristic, strong odor.
is the most common desiccated thyroid. It comes from pigs and is a mix of both thyroid hormones, triiodothyronine and thyroxine . There are few clinical trials on Armour Thyroid, meaning it has not been studied well. Additionally, and importantly, the FDA has not approved it for use.
Other brand names for desiccated thyroid are Nature-Throid, Westhroid, and NP Thyroid.
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How Quickly Does T3 Work
It can take weeks to feel the effects of added T3, but some people feel them right away.
Thyroid patient Leah felt immediate effects: “Within 20 minutes of taking my first dose of generic Cytomel, I was like a wilted flower put in water. On T3 I have my life back. I can hold down a full-time job I have enough energy to keep up with my grandchildren.”
What The Guidelines Say
Biancos view is particularly interesting because he co-chaired the task force that prepared ATAs latest hypothyroidism guidelines in 2014, which concluded that LT4 should remain the standard in treatment for hypothyroidism: We found no consistently strong evidence for the superiority of alternative preparations over monotherapy with levothyroxine in improving health outcomes. Even among patients who feel unwell on levothyroxine therapy alone, there is currently insufficient evidence to support the routine use of a trial of a combination of levothyroxine and liothyronine therapy outside a formal clinical trial.
We just dont have the data yet to change my mind that adding T3 to T4 actually results in a superior product. James V. Hennessey, MD, director of clinical endocrinology, Beth Israel Deaconess Medical Center, Boston, Mass.
The European Thyroid Association guideline says that combination therapy should be considered solely as an experimental treatment overseen by accredited internists/endocrinologists, and discontinued if no improvement is experienced after three months.
The most recently published guideline from the Italian Thyroid Association in late 2016 says that combination therapy is generally not recommended but a trial may be considered to improve adherence to treatment or patient well-being. Perhaps in a concession to reality, it outlines a protocol for combination therapy.
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What Should Be The Daily Dose Of Armour Thyroid
Having said that, I want to give you some idea as to what dose range you should be expecting when taking Armour thyroid. This way you know if you are likely being underdosed or overdosed. The average dose that most people need is somewhere between 1 grain and 2 grains per day. About 60-70%of individuals will fall into this range.
When Do You Know You Are Taking Too Much Armour Thyroid
If you are taking Armour thyroid and you find that your TSH is NOT decreasing then that is an indication that your dose is insufficient. This typically occurs when your doctor attempts to transition you from a thyroid medication such as levothyroxine to Armour.
You can switch to a different formulation of NDT such as NP thyroid or Nature-throid on a grain for grain basis. So, lets say you are currently taking 1.5 grains of Armour thyroid. If you wanted to switch to Nature-Throid you would switch over to 1.5 grains .
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Indications And Usage For Armour Thyroid
Armour® Thyroid tablets are indicated:
1. As replacement or supplemental therapy in patients with hypothyroidism of any etiology, except transient hypothyroidism during the recovery phase of subacute thyroiditis. This category includes cretinism, myxedema, and ordinary hypothyroidism in patients of any age , or state primary hypothyroidism resulting from functional deficiency, primary atrophy, partial or total absence of thyroid gland, or the effects of surgery, radiation, or drugs, with or without the presence of goiter and secondary , or tertiary hypothyroidism .
2. As pituitary TSH suppressants, in the treatment or prevention of various types of euthyroid goiters, including thyroid nodules, subacute or chronic lymphocytic thyroiditis , multinodular goiter, and in the management of thyroid cancer.
Thyroid hormone preparations are generally contraindicated in patients with diagnosed but as yet uncorrected adrenal cortical insufficiency, untreated thyrotoxicosis, and apparent hypersensitivity to any of their active or extraneous constituents. There is no well-documented evidence from the literature, however, of true allergic or idiosyncratic reactions to thyroid hormone.
Advantages To Custom Compounded Thyroid Medication
This is a distinct advantage of compounded Thyroid USP over other traditional alternatives. In terms of ingredient ratios and treatment purposes, Thyroid USP is the closest alternative to Armour Thyroid available in todays market. The experienced professionals of Keystone Pharmacy Compounding Pharmacy can compound dosages specific for your individual needs, and tailor the medication to personally fit your patient requirements. For additional information regarding Thyroid USP or any other products available through Keystone Pharmacys compounding program, please contact us today and we will be happy to serve you!
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How Can You Tell If You Are Sensitive To Armour Thyroid
Youll know if you are sensitive because you may experience side effects such as heart palpitations, a jittery or anxious feeling, or a headache after taking your dose. This doesnt automatically mean that you shouldnt take Armour thyroid , but instead may be a reflection of your sensitivity to the T3 found within the medication .
What Do The Sides Of Armour Thyroid Tablets Look Like
Armour Thyroid tablets are evenly colored, light tan, round tablets, with convex surfaces. One side is debossed with a mortar and pestle beneath the letter A on the top and strength code letters on the bottom as defined below.
While Armour Thyroid is a great medication it usually isnt enough for weight loss by itself. After all If weight loss were that simple, then Doctors would be prescribing low doses of Armour to every patient!
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Armour Thyroid Dosage And Administration
The dosage of thyroid hormones is determined by the indication and must in every case be individualized according to patient response and laboratory findings.
Thyroid hormones are given orally. In acute, emergency conditions, injectable levothyroxine sodium may be given intravenously when oral administration is not feasible or desirable, as in the treatment of myxedema coma, or during total parenteral nutrition. Intramuscular administration is not advisable because of reported poor absorption.
Do You Need To Dose Multiple Times Per Day
Another strategy to mitigate the potential side effects of Armour thyroid is to split your dose and take it multiple times throughout the day.
This is a strategy employed successfully by many people taking all types of thyroid medications .
The logic for using this strategy is simple:
A normal thyroid gland, when functioning correctly, secretes a small amount of thyroid hormone constantly throughout the day.
When you take thyroid medication by mouth you are taking one massive dose which is supposed to last all day.
This means that you are temporarily taking more than you need first thing in the morning and this large dose of thyroid hormone can cause problems for certain sensitive individuals.
You can combat this by splitting your dose in half and taking your dose in regular intervals throughout the day.
This reduces the massive flush which occurs from once a day dosing and may be ideal for some people, especially those who are sensitive to the T3 found within Armour.
Splitting your dose is actually very easy and shouldn’t cause any issues .
Let’s use an example:
Suppose that you are taking 2 grains of Armour thyroid per day.
Let’s also suppose that you are someone who is experiencing palpitations and flushing about 30-60 minutes after you take your medication.
You decide to alter how you take your medicine and split your dose into 2 divided doses.
You would proceed by taking 1 grain first thing in the morning around 7:00 am .
That would look something like this:
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Signs And Symptoms You Need T3
At least 15 percent of people in the United States treated for hypothyroidism still have unresolved symptoms. When you dont have enough T3 reaching your cells, you are functionally hypothyroid. The signs and symptoms can include fatigue, weight gain, depression, concentration and memory problems, hair loss, joint and muscle aches, dry skin, constipation, infertility, elevated cholesterol, erratic menstrual periods, and other signs of slow-downs in your key bodily functions.
What Are The Possible Side Effects Of Desiccated Thyroid
Common side effects may include temporary hair loss .
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
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How To Get Mail Order Armour Thyroid
SingleCare partners with GeniusRx to deliver mail order Armour Thyroid to your front door. With the SingleCare and GeniusRx home delivery program, when you mail order Armour Thyroid online, you save on your Armour Thyroid prescription and get Armour Thyroid delivered to your home. To get started with your Armour Thyroid mail order and start saving, click the button below.
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Each Person Is Different
Before we jump into the specifics, it’s important to realize that the dosing of thyroid medication is highly unique and individualized.
Each person will require a slightly different dose compared to the next person, even individuals who have the same body weight/metabolism/etc.
Having said that, I want to give you some idea as to what dose range you should be expecting when taking Armour thyroid. This way you know if you are likely being underdosed or overdosed.
The average dose that most people need is somewhere between 1 grain and 2 grains per day.
About 60-70% of individuals will fall into this range.
About 5-10% of people will need a dose less than 60mg per day .
About 10-20% of people will need a dose higher than 120mg per day .
These percentages are not perfect, but they are based on my own personal history in treating patients and discussing various doses with other doctors and practitioners.
Finding out where you fit into this spectrum can be difficult, but you can use the resources found here to help you find your optimal dose.
Thyroid By Erfa Canada
ERFA Canada has named their Health Canada regulated prescription-only product thyroid.
It is a porcine thyroid formulation that has approximately the same ratio of T3 and T4 found in American desiccated thyroid products like Armour and NatureThroid. According to the product monograph for Armour brand Thyroid, one grain, or 60 mg, provide 38 mcg levothyroxine and 9 mcg liothyronine .
Here is ERFA Canadas similar statement of what is usually considered equivalent:
This is also quite misleading, because the human body will absorb, transport and metabolize T4 and T3 differently when they are dosed at different combinations, or separately, either in the context of a persons partly functioning gland or their completely removed or non-functional thyroid gland.
In ERFA Canadas pamphlet, they then provide special dosing guides for children, followed by a table with adult dose equivalents across the three pharmaceuticals.
These statements presume a 1:4 ratio between T3 and T4 pharmaceuticals.
- 25 mcg of L-T3 = 100 mcg of L-T4 No, this is false in the human body.
- 50 mcg of L-T3 = 200 mcg of L-T4 No, this is false in the human body.
- 75 mcg of L-T3 = 300 mcg of L-T4 No, this is false in the human body.
Major clinical problems can arise with this limited, oversimplified math.
The scientists cannot see into cells and determine the amount of T3 that finally binds to receptors in the nuclei of cells under all pharmaceutical treatments, so where do they get these ideas?
The T4/t3 Thyroid Drug Controversy
As noted, the standard treatment for hypothyroidism is levothyroxine alone. The addition of T3 to the levothyroxine/T4-only treatmentor using DTEis controversial and the topic of ongoing research and discussion.
Once experts realized that T4 naturally converts to T3, there was a great deal of excitement about how modern levothyroxine was compared to DTE, which was considered old-fashioned. At that time, many healthcare providers switched patients over to the synthetic medication and never looked back.
Still, some of these patients complained after being switched to levothyroxine that their symptoms had worsened or couldn’t be resolved. This led to a number of the healthcare providers who had previously prescribed DTE for their patients putting some of them back on it.
DTE is prescribed far less often than levothyroxine. But frustrated patients who don’t feel well who are doing their research and talking to other people. As a result, they’re becoming increasingly aware that there are options beyond levothyroxine and that some people feel better on DTE.
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What Is The Unstated Basis Of These Equivalency Statements
Its a shame that the basis is not stated. Where is the published scientific study or studies that prove it?
In todays context, many will imagine that TSH response is the basis of this supposed equivalency . Many will mistake that a normalized TSH ought to be the sole target of therapy in each and every pharmaceutical modality.
In fact, TSH cannot be used as a judge of equivalency between these three pharmaceutical because of the unnatural response of the hypothalamus and pituitary to T3 dosing.
These tissues simply do not respond normally to fluctuating T3 levels, a fact that was noticed early on by the father of the TSH test, Robert Utiger . The hypothalamus and pituitary expect T3 to be continually secreted from a thyroid gland or converted from T4. Of course they must respond sensitively to the transient peak in Free T3 levels, because a high level could cause hyperthyroidism if the peak were not just a peak, but a constantly high level.
Therefore, dosed T3 creates peak FT3 levels in blood that artificially over-suppress TSH and can keep it suppressed even during the FT3 valleys between T3 doses .
Clearly, if TSH is the implicit judge of pharmaceutical equivalency, it is faulty. An abnormally lower TSH is a pharmaceutical side effect of T3-inclusive therapy on organs designed to regulate a functioning thyroid gland, not a sign of the effect of dosing on the entire human body.
NO, one cannot think this way.
Rlc Labs Inc Issues Voluntary Nationwide Recall Of All Lots Of Nature
September 3, 2020 RLC Labs, Inc. is voluntarily recalling a total of 483 lots of Nature-Throid® and WP Thyroid® in all strengths, all counts of product within current expiry to the consumer level. The products are being recalled because testing of samples from six lots by the U.S. Food and Drug Administration found the samples to be sub potent. The product may have as low as 87% of the labeled amount of Liothyronine or Levothyroxine.
Risk Statement: Patients being treated for hypothyroidism , who receive sub potent Nature-Throid® or WP Thyroid®, may experience signs and symptoms of hypothyroidism which may include, fatigue, increased sensitivity to cold, constipation, dry skin, puffy face, hair loss, slow heart rate, depression, swelling of the thyroid gland and/or unexplained weight gain or difficulty losing weight. There is reasonable risk of serious injury in newborn infants or pregnant women with hypothyroidism including early miscarriage, fetal hyperthyroidism, and/or impairments to fetal neural and skeletal development. In elderly patients and patients with underlying cardiac disease toxic cardiac manifestations of hyperthyroidism may occur, such as cardiac pain, palpitations or cardiac arrhythmia. RLC Labs, Inc. has not received any reports of adverse events related to this recall.
Consumers should contact their physician or healthcare provider if they have experienced any problems that may be related to taking or using this drug product.
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